Anna Modyil Mani was born on 23 August 1918 in Peermade, Kerala into an ancient Syrian Christian family. His father was a civil engineer.
In 1940, he received a scholarship for research at the Indian Institute of Science, Bangalore. In 1945, she went to Imperial College, London to pursue her graduation in Physics. However, she had gained expertise in meteorological instruments.
Anna Mani wanted to make India independent in weather instruments. He standardized the drawings of about 100 different weather instruments.
The World Meteorological Organization remembered him on his 100th birth anniversary and published his life profile with Anna Interview.